Related articles by
Research Idea
Research Ideas and Outcomes 10: e120899
https://doi.org/10.3897/rio.10.e120899 (22 Mar 2024)
https://doi.org/10.3897/rio.10.e120899 (22 Mar 2024)
- ContentsContents
- Article InfoArticle Info
- CiteCite
- MetricsMetrics
- CommentComment
- RelatedRelated
- FigsFigs
- TabsTabs
- TaxaTaxa
- RefsRefs
- CitedCited
- NanopubsNanopubs
- Reviews2Reviews
-
Article metadata
-
Introduction
-
Background
-
Reported Reduced Praziquantel Efficacy
-
Mechanism of action of PZQ
-
Molecular Determinants of PZQ resistance
-
Diagnostic approaches for PZQ resistance
-
-
-
Aim
-
Objectives
-
-
Problem Statement and Rationale
-
Methodology
-
Ethical Approval
-
Study population and sample collection
-
Identification of resistance markers in lab-generated resistance models for intermediate (snail), definitive host (mice) and eggs
-
Investigation of effects of PZQ resistance via CRISPR-Cas9-mediated genome editing with functional markers from objective 1
-
Molecular diagnostic tool development with selected resistant markers
-
Field testing and assessment of the developed diagnostic tool in selected schistosomiasis-endemic communities
-
Data Analysis
-
-
Expected Outcomes
-
References
Subscribe to email alerts for current Article's categories