Latest Articles from Research Ideas and Outcomes Latest 8 Articles from Research Ideas and Outcomes https://riojournal.com/ Thu, 28 Mar 2024 14:34:42 +0200 Pensoft FeedCreator https://riojournal.com/i/logo.jpg Latest Articles from Research Ideas and Outcomes https://riojournal.com/ PoshBee: Pan-European Assessment, Monitoring, and Mitigation of Stressors on the Health of Bees https://riojournal.com/article/72163/

DOI: 10.3897/arphapreprints.e72231

Authors: Mark Brown, Tom Breeze, Philippe Bulet, Marie-Pierre Chauzat, Iliyana Demirova, Joachim de Miranda, Alexandra-Maria Klein, Marika Mand, Teodor Metodiev, Denis Michez, Franceso Nazzi, Peter Neumann, Robert Paxton, Simon Potts, Jane Stout, Gail Turney, Orlando Yañez

Abstract: PoshBee is a 5-year funded project (2018-2023) that aims to support healthy bee populations, sustainable beekeeping, and consequently pollination for crops and wildflowers across Europe. To do this we take a range of approaches, from the laboratory to the field, from molecules to ecosystems, and from fundamental science to risk assessment. This document is an edited version of the original funding proposal that was submitted to the European Commission.

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Grant Proposal Tue, 17 Aug 2021 16:30:00 +0300
Rethinking schizophrenia through the lens of evolution: shedding light on the enigma https://riojournal.com/article/28459/ Research Ideas and Outcomes 4: e28459

DOI: 10.3897/rio.4.e28459

Authors: Ariel Cariaga-Martinez, Kilian Gutiérrez, Raúl Alelú-Paz

Abstract: Schizophrenia refers to a complex psychiatric illness characterized by the heterogenic presence of positive, negative and cognitive symptoms occurring in all human societies. The fact that the disorder lacks a unifying neuropathology, presents a decreased fecundity of the affected individuals and has a cross-culturally stable incidence rate, makes it necessary for an evolutionary explanation that fully accounts for the preservation of “schizophrenic genes” in the global human genepool, explaining the potential sex differences and the heterogeneous cognitive symptomatology of the disorder and is consistent with the neuropsychological, developmental and evolutionary findings regarding the human brain. Here we proposed a new evolutionary framework for schizophrenia that is consistent with findings presented in different dimensions, considering the disorder as a form of brain functioning that allows us to adapt to the environment and, ultimately, maintain the survival of the species. We focus on the epigenetic regulation of thalamic interneurons as a major player involved in the development of the clinical picture characteristic of schizophrenia.

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Research Idea Thu, 19 Jul 2018 09:41:44 +0300
Origin and diversification of hoverflies: a revision of the genera Asarkina and Allobaccha – A BIG4 Consortium PhD project https://riojournal.com/article/19860/ Research Ideas and Outcomes 3: e19860

DOI: 10.3897/rio.3.e19860

Authors: Trevor Burt, Ximo Mengual

Abstract: This BIG4 PhD project involves the overall taxonomic revision of the genera Allobaccha Curran and Asarkina Macquart (Diptera: Syrphidae). The revisions will be divided by biogeographic region (Afrotropical and Indomalayan) and published accordingly. The publications will be collated as a thesis for submission to the University of Bonn (Rheinische Friedrich-Wilhelms-Universität Bonn, Germany) doctoral program of biology. The goal of this project is to resolve alpha taxonomy and to infer the phylogenetic placement of these genera within the Syrphidae using Next-Generation Sequencing and Anchored Hybrid Enrichment techniques. The techniques undertaken in this project will be applied to future systematic problems in Diptera and testing future phylogenetic hypotheses.

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PhD Project Plan Mon, 7 Aug 2017 13:57:28 +0300
Functional characterization of the several splice variants of Fmr1 https://riojournal.com/article/10593/ Research Ideas and Outcomes 2: e10593

DOI: 10.3897/rio.2.e10593

Authors: Megha Abbey

Abstract:

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Research Idea Wed, 28 Sep 2016 10:22:21 +0300
Matrix Proteins and Proteinases Network in Human Cardiovascular Diseases Explored By Cytoscape https://riojournal.com/article/9617/ Research Ideas and Outcomes 2: e9617

DOI: 10.3897/rio.2.e9617

Authors: Robert Chen, Wei-hsuan Yu

Abstract: Matrix proteins and proteinases altered extracellular matrix that involves in various pathogenesis of cardiovascular diseases. Systematic review selected matrix metalloproteinase-7 (MMP7), a disintegrin and metalloproteinase-17 (ADAM17), type I collagen (COL1), syndecan (SDC), and versican (VCAN). Their network was drawn by Cytoscape and Agilent Literature Search. MMP7, ADAM17, and SDC were grouped together. VCAN and COL1 had inadequate evidence to connect their human potential networks that were more evidence in animal models. The findings may provide clues for further laboratory investigations.

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Single-figure Publication Mon, 27 Jun 2016 17:42:46 +0300
Synthetic epidermal growth factor receptor (EGFR)-mitochondria desired axles-based split green-fluorescent-protein (GFP) could screen for the signaling molecules that overcome the drug resistance to tyrosine kinase inhibitor (TKI) https://riojournal.com/article/9551/ Research Ideas and Outcomes 2: e9551

DOI: 10.3897/rio.2.e9551

Authors: Robert Chen, Wei-hsuan Yu

Abstract:

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Conference Abstract Thu, 23 Jun 2016 11:25:12 +0300
Chimeric spider silk production in microalgae: a modular bionanomaterial https://riojournal.com/article/9342/ Research Ideas and Outcomes 2: e9342

DOI: 10.3897/rio.2.e9342

Authors: João Vitor Molino, Tiago Lubiana Alves, Livia Ferreira-Camargo, Miguel Croce, Allan Tanaka, Felipe Buson, Pedro Ribeiro, Antony Campos-Salazar, Eduardo Antonio, André Maizel, Viviane Siratuti, Claudia Costa, Samarina Wlodarczyk, Raquel de Souza Lima, Fabio Mello, Stephen Mayfield, João Carvalho

Abstract:

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Research Idea Thu, 23 Jun 2016 10:33:17 +0300
Bi-directional immuno-modulation by Matrix Metalloproteinase-7 (MMP-7) and A Disintegrin And Metalloproteinase-17 (ADAM-17) as transplantation rejection-tolerance spectrum https://riojournal.com/article/9268/ Research Ideas and Outcomes 2: e9268

DOI: 10.3897/rio.2.e9268

Authors: Robert Chen

Abstract:

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PhD Project Plan Thu, 26 May 2016 15:03:37 +0300