"Key Output 1. Conceptual framework" "Scale: TIER2’s conceptual framework has the potential to expand understanding of reproducibility gains & savings across epistemic contexts. Doing so will enable realistic mapping of impact pathways of reproducibility interventions across disciplines & regions, empowering effective decision-making for RPOs, funders & publishers. This framework also consolidates state-of-the-art evidence/advice on existing tools & practices that will be used by more than 1000 researchers during TIER2 & many thousands more afterwards.Significance: These two contributions enable significant efficiency- & quality-gains through informed future policy. The results provided in this task will be applicable to a large range of research, with our case studies/pilot activities covering three key domains (computer, life, & social sciences). Results will be applicable to researchers in these domains, as well as publishers & funders on a global scale.Key barrier: Framework too theoretical & not applicable to real-life contextsMitigation: TIER2 uses co-creation with relevant stakeholders & evidence accumulated throughout the project to inform development of the framework & ensure real-world relevance/impact." "Key Output 2. Innovative Tools & practices for diverse contexts" "Scale: TIER2 will develop 8 new tools & practices for researchers, funders, institutions, & publishers, which will be applicable to key disciplinary areas & ready for extension to many more after the project. The impact of these tools over the long-term will be immeasurable. We expect, for example. our Reproducibility Promotion Plans for funders to become a de facto standard for priority planning, & our workflows for review of data/code will be instrumental in ensuring & validating the reproducibility & re-usability of those objects.Significance: Our tools target all elements of the research lifecycle from project planning to assessment & hence are of relevance to many thousands of researchers, funders & publishers. Closely aligning these tools with the Embassy of Good science & EOSC will result in fast & efficient uptake.Key barrier: Tools/practices not fit for purposeMitigation: We have selected this provisional list of tools as priorities for development based on state-of-the-art evidence (sec. 1.2). They will be refined, developed & piloted through co-creation with users, & a solid framework for assessment will be used to evaluate & showcase efficacy. Targeted exploitation & dissemination measures, including via our Reproducibility Hub & EOSC will ensure uptake." "Key Output 3. Increased Capacity" "Scale: National Reproducibility Networks are powerful networks which reach directly to institutions & across Europe & the globe. Growing aligning this with infrastructural investments like EOSC (250m EUR invested 2018-2020*14), & international networks of funders, publishers & RPOs, mean TIER2 will have powerful multiplier effects in building capacity. Our training & skills resources, hosted for the long-term by the sustainable Embassy of Good Science (over 2500 monthly visitors) will develop further awareness amongst individuals & bring them into this community, meaning that TIER2 will potentially affect the reproducibility practices of hundreds of thousands in the years after the project.Significance: Under this objective, practical policy & implementation recommendations/guidelines for research funders, institutions, policy-makers, publishers & researchers in Europe & beyond will be developed. The recommendations & guidelines will reach a minimum of 1000 researchers, we aim for adoption of our policy recommendations in at least 4 funders, & 2 publishers through the dissemination activities outlined under section 2.2. This will lead to increased awareness among those stakeholders, & to concrete changes, jump-started by the pilot implementations. We expect pilot activities to be taken up well by stakeholders, given the co-created approach taken to the pilots. We therefore further expect 4 funders & 2 main publishers to continue using the tools & practices developed throughout the project, maximising impact via their own reach.Key barrier: Increased capacity not carried forward once project-funding & TIER2 activities are overMitigation: By seeking to embed our gains in the interlinking of the RNs & EOSC, which both will only grow in importance in the coming years, we are certain our capacity-gains will be sustainable for the long-term, also enabled via our teaming with funder-groups like Science Europe & EVIR (to foster Reproducibility Promotion Plans) as well as publisher-groups like STM Association." "Key Output 4. Policy roadmap (guidelines & recommendations)" "Scale: Key themes in TIER2 are epistemic diversity, the need to discern Impact Pathways to optimise reproducibility, & collaboration for network effects. Carrying these into the future will be heavily influenced by the success of our policy recommendations. If done well, they will bind stakeholders in collaborative action to optimise reproducibility in the right ways for the right contexts. This will ensure the prioritisation of reproducibility as a policy priority for funders, publishers, RPOs & others, having the potential to sustain & amplify TIER2’s gains for the long-term.Significance: We started by noting a conservative calculation that enabling a 1% increase in Horizon Europe would result in savings of 100m EUR. Extrapolating such figures to the global R&I system shows the massive potential significance of TIER2, if momentum & direction is sustained in the correct way beyond the project. Our policy recommendations, co-created with stakeholders, will ensure this happens.Key barrier: Low acceptance of policy recommendations amongst major stakeholdersMitigation measure: TIER2 is community-based from the start. Through co-developing our framework & tools with stakeholders, to targeted capacity-building actions, & finally co-creating the recommendations with stakeholders, we are assured the recommendations target the reproducible future stakeholders wish to see. An effective & dedicated exploitation & dissemination plan, in which major stakeholders not already involved in recommendation co-creation are kept informed & engaged, will ensure maximal impact upon release & into the future."