Structural analysis of SARS-CoV spike glycoprotein. In A the SARS-CoV spike protein (PDB ID: 6ACG) is shown bound to ACE2 (brown) and 80R antibody (cyan), superimposed on the same binding site. In B the spike protein is shown bound only to the 80R antibody (PDB ID: 2GHW), with the structural model of the RBD of the SARS-CoV-2 spike protein (magenta) containing the missing loops. This homology model served as the basis for the docking experiments. In C it is shown a spike colored by subunit and showing the glycans. There are only two possible glycans in RBD region at 331 and 343 and neither of these sites affect the 80R binding.

 
  Part of: Padilla-Sanchez V (2020) In silico analysis of SARS-CoV-2 spike glycoprotein and insights into antibody binding. Research Ideas and Outcomes 6: e55281. https://doi.org/10.3897/rio.6.e55281